Laboratory: Clinical Biochemistry
Test Name:
MEXILETINE - Alternate Name: PROZAC - (P) or (S)
Test Code: MXLT
Clinical Information:
Patient preparation instructions:

Specimens should only be collected after patient has been receiving mexiletine for at least 3 days. Trough concentrations should be collected just before administration of the next dose.

Collection Devices:
Preferred Device:
2 - Serum Tube(s), NO GEL - Full Tube Collection



Serum Tube(s), NO GEL - Full Tube Collection
Manufacturer: Becton Dickinson

Catalogue #: 366430
 - Specimens that are obtained from gel tubes or anticoagulate collections can cause assay interference.
Do not use separator gel.
Specimen Required:


Plasma: 3.0 mL

Specimen Stability:

Ambient: 28 days

Refrigerated: 28 days

Frozen: 28 days

Referral:

Referred Out Location: Mayo Clinic Laboratories - Test code: MEX
Requisition:
Reference Values:
Therapeutic concentration:    0.8 - 2.0 μg/mL  (trough value)
 
Toxic concentration:             >2.0 μg/mL  (trough value)      


Method of Analysis: Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Availability:
Within 1 Week
See Also:
More Information:
Send refrigerated to Mayo Medical Laboratories.