View Test

Laboratory:

Clinical Biochemistry

Test Name:

METHYLMALONIC ACID - (P)

Test Code: MISC

Clinical Information:

Test Indications: This test is used for evaluating children with signs and symptoms of methylmalonic acidemia.

This test is also used for evaluating individuals with signs and symptoms associated with cobalamin deficiency (vitamin B12).

Test Approval Requirements:

Approval Is not required for patients <19 years. For adults (≥19y) testing is restricted without approval to following specialties: hematology, oncology, neurology, and genetics. All other requests require test approval. Click here for the Approval for Test Referral Biochemistry for (F260-11-02).

Collection Devices:

Preferred Device:	1 - EDTA 6 mL NO GEL Tube(s) - Full Tube Collection EDTA 6 mL NO GEL Tube(s) - Full Tube Collection Manufacturer: Becton Dickinson & Company Catalogue #: 367863
Alternate Device:	1 - Serum Tube(s), NO GEL - Full Tube Collection

SST serum (Gold top) is also acceptable

Specimen Required:

Plasma: 3.0 mL

Pediatric Plasma: 3.0 mL

Separate within 6 hours of collection. Store and send frozen.

Ambient: 8 hours

Refrigerated: 7 days

Frozen: 28 days

Referral:

Specimen referred from HSC-MS5 to:

In-Common Laboratories (ICL)
57 Gervais Drive
North York, Ontario
M3C 1Z2
Telephone: (416) 422-3000
Test ID: MMA P
Test Name: Methylmalonic Acid, Serum/Plasma

Requisition:

_SH Biochemical Genetics Laboratory Requisition (R250-10-69)

Reference Values:

0.10 – 0.40 umol/L

Values up to 2.0 µmol/L are not uncommon in patients with renal failure or systemic disease without evidence of Vitamin B12 deficiency.

Availability:

Within 2 Weeks