Laboratory: Clinical Immunology
Test Name:
Test Code: MIS8
Clinical Information:
Neutropenia results from either under production or increased destruction.  Neutropenia due to increased destruction is often caused by antibodies that bind to the neutrophils and hasten their clearance from their circulation.  Antibodies can form against neutrophil-specific alloantigens and neutrophil antigens shared with other cells.  Neutrophil antibodies are important in clinical conditions including neonatal alloimmune neutropenia, autoimmune neutropenia, transfusion-related acute lung injury (TRALI), and drug-induced neutropenia.
Collection Devices:
Specimen Required:
Serum: 5.0 mL
Pediatric Serum: 1.0 mL

Forward sample to Central Services, MS5, HSC for referral. 
Ship overnight, labelled "Refrigerate upon arrival" to:
Versiti Diagnostic Laboratories/Client Services
638 North 18th Street
Milwaukee, WI  53233-2121

Sample is stable for 7 days refrigerated.  If testing cannot be completed within 7 days, sample must be stored and shipped frozen.
Reference Values:
Within 10 Days
Restricted to Pediatric Hematologists or by prior approval.
See Also:
More Information: