| Laboratory: | Clinical Immunology |
| Test Name: |
GLOMERULAR BASEMENT MEMBRANE ANTIBODY - IgG - (S)
Test Code:
GBM
|
| Clinical Information: |
Testing is performed at St. Boniface Hospital Immunology Lab using an indirect Immunofluorescence assay (IFA). Serum samples are initially screened at a 1:10 dilution utilizing frozen sections of primate kidney as well as highly purified antigen.
This test provides semiquantitative in vitro determination of human antibodies of immunoglobulin class IgG against glomerular basement membrane in patient samples to support the diagnosis of Goodpasture syndrome and glomerulonephritis. |
| Collection Devices: |
Preferred Device:
|
| Specimen Required: |
Blood: 5.0 mL
Serum: 1.0 mL
|
| Referral: |
Serum: 1.0 mL
Separate serum and ship refrigerated, or frozen if greater than 7 days from time of collection.
|
| Requisition: | |
| Reference Values: |
GBM: <1:10 Titre (Negative)
Positive results will also be accompanied by a titre. A negative result does not necessarily exclude autoimmune disease. Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings. |
| Availability: |
Weekdays
TAT 5-7 Days
|
| See Also: | |
| More Information: |