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Laboratory:

Clinical Biochemistry (METABOLIC)

Test Name:

CITRATE – Random (Citrate/Creatinine Ratio) - (U)

Test Code: CITU

Clinical Information:

Description: ONLY FOR PEDIATRICS

Test Indications: 24-hour collection is the preferred specimen for measuring and interpreting citrate levels. Random collections normalized to urinary creatinine may be of some clinical use in pediatric patients who cannot collect a 24-hour specimen. Random samples from patients >17 years of age are not accepted

Urinary citrate is a major inhibitor of kidney stone formation due in part to binding of calcium in urine. Low urine citrate levels are considered a risk for kidney stone formation.

Collection Devices:

Preferred Device:	1 - Urine Collection Container, Random 100 mL Urine Collection Container, Random 100 mL Manufacturer: Starplex Scientific Inc. (Etobicoke, ON) Catalogue #: 3008-1
Alternate Device:	1 - Urine Collection 12 mL Tube Urine Collection 12 mL Tube Manufacturer: Sarstedt Canada Inc. (vendor) Catalogue #:

Specimen Required:

Urine: 10.0 mL

Pediatric Urine: 5.0 mL

No preservative is required

Referral:

Urine: 10.0 mL

Pediatric Urine: 5.0 mL

Refer to
JA110-50-01A 24 Hour Urine Processing Flow Chart
JA110-50-01B Random Urine Processing Flow Chart

Specimen Stability:

Refrigerated: 14 Days

Frozen: 14 Days

Testing Laboratory (MB): St. Boniface Lab

Requisition:

_SH Urine Testing Requisition (R250-10-95)

Reference Values:

Citrate Random Urine
Age	Normal Range (mmol citrate/mmol creatinine)
< 1 m	reference ranges not established
1 - 11 m	0.14 - 2.41
1 - 9 yr	0.07 - 0.67
10 - 17 yr	0.03 - 0.50
>17 y	reference ranges not established

Method of Analysis: Enzymatic

Availability:

Within 10 Days