Laboratory: Clinical Biochemistry
Test Name:
ALPHA-FETOPROTEIN (AFP) - (CSF)
Test Code: MSFL
Clinical Information:
Test Indications: This test is used for the diagnosis and management of intracranial germ cell tumors.
Recommendations: An Update on the Clinical Diagnostic Value of Beta-HCG and AFP for Intracranial Germ Cell Tumors. Eur J Med Res 2016, 21:10
Patient Preparation Instructions: Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose.
Additional Information: The test method used is an Electrochemiluminescence (ECLIA) assay manufactured by Roche Diagnostics Inc. and performed on the Cobas Elecsys system.
Patient results determined by different assay manufacturers or methods are not comparable and cannot be used interchangeably for patient monitoring.
Collection Devices:
Specimen Required:


Cerebrospinal Fluid: 1.0 mL

Stability 24 hours refrigerated, 7 days frozen
Referral:

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
Requisition:
Reference Values:
≤ 1.0 µg/L
Availability:
Daily or Stat
See Also:
More Information: