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Laboratory:

Clinical Biochemistry

Test Name:

PROSTATE SPECIFIC ANTIGEN (PSA) RATIO, FREE/TOTAL (CALCULATION)

Test Code: None

Clinical Information:

When tPSA is >4 μg/L, a fPSA/tPSA ratio of >0.25 is associated with an increased probability of being cancer-free.

When tPSA is <4 μg/L, a lower fPSA/tPSA cutpoint of 0.10 detects more cancers.
When tPSA is above 10 μg/L, the risk of prostate cancer is relatively high and use of fPSA/tPSA ratio is not recommended as it provides little additional discriminating power.

Collection Devices:

Specimen Required:

Referral:

Requisition:

Reference Values:

> 0.25

Availability:

Calculated when both Free PSA and Total PSA performed. Available to Urologists only.

Laboratory:	Clinical Biochemistry
Test Name:	PROSTATE SPECIFIC ANTIGEN (PSA) RATIO, FREE/TOTAL (CALCULATION) Test Code: None
Clinical Information:	When tPSA is >4 μg/L, a fPSA/tPSA ratio of >0.25 is associated with an increased probability of being cancer-free. As the fPSA/tPSA ratio decreases, the probability of prostate cancer increases. When tPSA is <4 μg/L, a lower fPSA/tPSA cutpoint of 0.10 detects more cancers. When tPSA is above 10 μg/L, the risk of prostate cancer is relatively high and use of fPSA/tPSA ratio is not recommended as it provides little additional discriminating power.
Collection Devices:
Specimen Required:
Referral:
Requisition:
Reference Values:	> 0.25
Availability:	Calculated when both Free PSA and Total PSA performed. Available to Urologists only.
See Also:	PROSTATE SPECIFIC ANTIGEN, FREE (FREE PSA) - (P)
More Information: