Laboratory: Clinical Biochemistry  (SENDOUTS)
Test Name:
L-ASPARAGINASE ACTIVITY - (P)
Test Code: MIS8
Clinical Information:
Test Indications:  This test is indicated to monitor L-asparaginase activity in children with acute lymphoblastic leukemia (ALL) receiving PEG-Asparaginase.
Recommendations:   This test is only ordable by Peadiatric Oncologists. All requests require Biochemist approval. Use form F260-11-02 Biochemistry Approval for Test Referral to request approval. 
Collection Devices:
Specimens that are obtained from gel tubes are not acceptable and will be rejected.
Specimen Required:

Collection Information: Collect sample prior to administration of next dose. Indicate date and time of last dose and daily dosage. Write down the type of asparaginase given to the patient (Oncaspar, Kidrolase, Erwiniase).
Referral:

Referred Out Location: In Common Laboratories
Requisition:
Reference Values:
Method of Analysis: Microplate Reader-Based Method
Availability:
Within 2 Weeks
See Also:
More Information:
Centrifuge the blood sample at 1100-1300 x g for 10 minutes at 25º C. Vial labels must include
the name of the patient, date and time the specimen was collected, type of sample (serum
or plasma) and the form of L-asparaginase received by the patient (EColi, Erwinia or
PEG) .Immediately place the cryotube in a freezer maintained at -70 ºC or lower until packaged for shipment.
Samples stored at room temperature for longer than 2 hours are not suitable for testing and will be rejected. Frozen samples should be shipped on Dry ice to:

In Common Laboratories