Laboratory: Clinical Biochemistry  (TOXICOLOGY)
Test Name:
COTININE - (U)
Test Code: DRUG
Clinical Information:
Alternate Name(s): Nicotine metabolite, Comprehensive Drug Screen-(U)

Description: Test to be used for transplant patient screening for cotinine, which is the major nicotine metabolite from tobacco. This test is a component of the Comprehensive Drug Screen. Specific comment for cotinine will be reported for transplant patients, if a request for cotinine testing for reason of transplant is listed on the ordering requisition. 

Test Indications: See below for list of drugs detected by this method, note this list is revised periodically.

Recommendations: Results are for medical diagnostic purposes only. Test results are presumptive. No chain of custody in collection and transportation of sample for testing. Not suitable for employment or legal purposes or other statutory regulations.
Collection Devices:
Specimen Required:
Urine: 3.0 mL

Specimen Stability: 
Refrigerated: Samples should be stored and sent refrigerated if delivered within 7 days.
Frozen: Samples need to be frozen if delivery to lab exceeds 7 days.
Other comments:  Specimen received greater than 30 days post collection will not be tested
Referral:
Urine: 3.0 mL

Shipping & Storage: Samples should be stored and sent refrigerated if delivered within 7 days. Samples need to be frozen if delivery to lab exceeds 7 days.
Other Comments: Aliquot 3.0 ml into Greiner aliquot tube. 
See JA110-50-01B Random Urine Processing Flow Chart
Requisition:
Reference Values:
Reference Intervals: Drugs and metabolites detected will be listed on report if present. For cotinine determination in transplant patients, “No Cotinine Detected” will be reported if cotinine is not detected.
Click hyperlink for the list of drugs detected:
Method of Analysis: Test performed at: St. Boniface Hospital by Shared Health Toxicology Laboratory using Liquid Chromatography-Accurate Mass Spectrometry with targeted analysis. This is a laboratory developed test. 
Availability:
See Also:
More Information: