Laboratory: Clinical Biochemistry  (METABOLIC)
Test Name:
PORPHYRINS EVALUATION - (B)
Test Code: MISC
Clinical Information:
Alternate Names: 
Erythrocyte Porphyrin
Erythropoietic Protoporphyria (EPP)
Free Erythrocyte Porphyrin (FEP)
Protoporphyrin
Protoporphyrins, Total, Erythrocytes
RBC Porphyrins
Red Blood Cell Porphyrins
X-linked Dominant Protoporphyria (XLDPP or XDP)
Description: Establishing a biochemical diagnosis of erythropoietic protoporphyria and X-linked dominant protoporphyria.
 
If the total erythrocyte porphyrin value is 80 mcg/dL or above, the protoporphyrin fractionation assay will automatically be performed.

Test Indications:This is the preferred test for assessment for protoporphyria.
This test is not suitable for individuals with bullous dermatosis who are in chronic renal failure and unable to provide a urine specimen. Please contact the duty clinical biochemist for more information.
Test Approval Requirements: F260-11-02 Biochemistry Approval for Test Referral Form
Recommendations: Include a list of medications the patient is currently taking.
Patient preparation instructions: Patient should abstain from alcohol for 24 hours.
Alcohol suppresses enzyme activity potentially leading to false-positive results if it is ingested within 24 hours of specimen collection
 
Collection Devices:
EDTA 4 mL NO GEL Tube(s) - Full Tube Collection
Specimen Required:

Whole Blood:
Adult: full tube
Pediatric: min. 3 mL 

Collection Information: Immediately place specimen on wet ice and transport to the lab
Special Processing: Do NOT centrifuge samples.
Specimen Stability:
Ambient: N/A
Refrigerated: 7 days
Frozen: N/A
Other Comments: Grossly hemolyzed sample rejected
Referral:

Shipping & Storage: Keep, store and send the sample refrigerated without delay to Health Sciences Center (HSC)
Testing Laboratory (MB): Send out testing
Referred Out Location: Mayo Clinic Laboratories, Test ID: PEE
Requisition:
Reference Values:
Method of Analysis: Spectrofluorometry
Availability:
One week
See Also:
More Information: