| Laboratory: | Clinical Immunology |
| Test Name: |
OXIDATIVE BURST - (B)
Test Code:
OBRT
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| Clinical Information: |
Chronic Granulomatous disease (CGD) is an inherited primary immunodeficiency disorder characterized by severe, recurring infections with formation of granulomas. Phagocytic cells ingest, but cannot digest bacteria or fungi due to a malfunction of the nicotinamide adenosine dinucleotide phosphate (NADPH) oxidase system.
Patients treated with acetaminophen have decreased neutrophil oxidative burst as measured by DHR testing. To avoid falsely abnormal testing for CGD, patients should be advised to avoid acetaminophen for at least 24 hours prior to DHR testing. |
| Collection Devices: |
Preferred Device:
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| Specimen Required: |
Blood: 4.0 mL
Microtainer collections are not suitable for testing and will be rejected. |
| Referral: |
Must be processed within 24 hours of collection. Ship and store at ambient temperature. A copy of a CBC collected at the same time should also be included.
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| Requisition: | |
| Reference Values: |
A descriptive report will be issued.
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| Availability: |
Weekdays (Mon to Thurs)
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| See Also: | |
| More Information: |
Microtainer collections are NOT suitable for testing and will be rejected.
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