Laboratory: Clinical Biochemistry
Test Name:
CEROID LIPOFUSCINOSIS - (B)
Test Code: MISM
Clinical Information:
Includes testing for CLN 1 gene (Palmitoyl-protein thioesterase I (PPT) and CLN 2 gene (Tripeptidyl Peptidase I (TPP).  Include both hospital requisition and Seattle Children’s Hospital Biochemical Genetics requisition.
Collection Devices:
Specimen Required:

3 - 4 circles of dried blood on a newborn screening card
Referral:

3 - 4 circles of dried blood on a newborn screening card
Requisition:
Reference Values:
Palmitoyl-Protein Thioesterase I (PPT): 21 - 56 pmol/h/spot         
Tripeptidyl Peptidase I (TPP): 60 - 162 pmol/h/spot                          
Availability:
Within 3 Weeks
See Also:
More Information:
HSC Clinical Chemistry will refer to Department of Laboratories, Children’s Hospital & Regional Medical Center, 4800 Sand Point Way N.E., Seattle, Washington 98105  (Ph. 206-987-2102).
If heparinized blood is submitted, spot 3-4 circles on a newborn screening card.  Dry spots and submit for testing. 
XBATT