| Laboratory: | Clinical Biochemistry | ||||||||||||||||||||||||||
| Test Name: |
ALBUMIN - (U)
Test Code:
UALB
|
||||||||||||||||||||||||||
| Clinical Information: |
Test performed at: St. Boniface Hospital, Health Sciences Centre and Westman Laboratory
Albumin is a non-glycosylated protein synthetized by liver parenchymal cells. Quantitatively, albumin is normally the most important protein component in plasma (>50%), CSF and urine. A small, but abnormal albumin excretion in urine is known as microalbuminuria. Causes of microalbuminuria can be glomerular, tubular or post renal. Albumin is also a marker for various forms of proteinuria. Recommendations: The random urine to creatinine ratio (urine ACR) is the test of choice when screening for albuminuria as it predicts 24 hour urinary albumin excretion sufficiently well. The diagnosis of albuminuria requires the elevated urinary albumin to be persistent. Due to biologic variability at least 2 of 3 elevated levels collected over a 3 month period are required for the diagnosis of albuminuria. For guidelines see Chronic Kidney Disease in Diabetes. Diabetes Canada 2018 Clinical Practice Guidelines. Can J Diabetes 2018, 42: S201-S209 |
||||||||||||||||||||||||||
| Collection Devices: |
Collect without preservative. Refrigerate 24h and random urine specimens until analysis.
Similar lab approved leak-proof containers acceptable. |
||||||||||||||||||||||||||
| Specimen Required: |
Urine: 3.0 mL
Stability 1 month refrigerated, 6 months frozen |
||||||||||||||||||||||||||
| Referral: | |||||||||||||||||||||||||||
| Requisition: | |||||||||||||||||||||||||||
| Reference Values: |
|
||||||||||||||||||||||||||
| Availability: |
Weekdays
|
||||||||||||||||||||||||||
| See Also: | |||||||||||||||||||||||||||
| More Information: |
If random urine, specify. If 24 h urine, measure and record volume. Refrigerate 24h and random urine specimens until analysis.
|