Laboratory: Clinical Immunology
Test Name:
Test Code: PCA
Clinical Information:
Test performed at:  St. Boniface Hospital, Immunology Lab, using and indirect Immunofluorescence assay (IFA).  Serum samples are initially screened at a 1:10 dilution.
This test kit provides semiquantitative in vitro determination of human antibodies of immunoglobulin class IgG against parietal cells in patient samples to support the diagnosis of chronic-atrophic gastritis, pernicious anemia, funicular myelosis,  and various autoimmune endocrinopathies.
Collection Devices:
Specimen Required:
Blood: 5.0 mL

Serum: 1.0 mL
Serum: 1.0 mL

Separate serum and ship refrigerated or frozen if greater than 7 days from time of collection.
Reference Values:
PCA:  <1:10 Titre (Negative)
A negative result does not necessarily exclude autoimmune disease.  Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings.
Laboratory Hours of Operation: Mon-Fri, 0800-1615, excluding holidays. PCA TAT: within 10 days
See Also:
More Information:
Positive results will also be accompanied by a Titre.
Autoantibodies against mitochondria (AMA) may lead to incorrect evaluation results. The substrate primate stomach is therefore preincubated with glycine urea buffer to reduce AMA-specific fluorescence.
Serum Separator (SST) Tube(s) - Full Tube Collection
Manufacturer: Becton Dickinson

Catalogue #: 367986