Description: Clinicians may request molecular genetic testing for diagnosis, prevention, familial variant testing, and/or treatment purchases, that is currently not available within Shared Health Cytogenetic or Molecular Diagnostic Laboratories. 
 

Process for Clinicians:

1. Obtain and document informed consent.

2. For a prenatal diagnosis, contact Lab Genetic Counsellor for prior approval, requisition, and specimen requirements.

3. For whole exome sequencing request refer to WHOLE EXOME SEQUENCING.

4. Complete the R250-10-103 Molecular Diagnostics Laboratory – Out of Center Genetic Test Requisition.

The following information must be provided:

a. Preferred referral laboratory (note: the Molecular Diagnostic Laboratory reserves the right to select an alternate referral laboratory)

b. Referral lab’s test order code

c. If request is urgent (e.g. results would impact urgent medical management OR management of an affected or at-risk pregnancy)

d. All relevant patient and family information

5. Collect the patient specimen.

6. Submit specimen and completed R250-10-103 Molecular Diagnostics Laboratory – Out of Center Genetic Test Requisition to laboratory for holding until approved.

Some requests for out of centre genetic testing may be reviewed for approval by the Shared Health Genomics Out of Centre Genetics Testing Committee. Each test request will be evaluated regarding the availability of the genetic test requested, whether the patient meets appropriate testing criteria, and if there is funding available.
 

Approved requests: Ordering provider will be contacted by a laboratory Genetic Counsellor for additional information regarding sample and requisition requirements. The whole exome sequencing test may be sent for to a referral laboratory for testing, or tested in-house, at the molecular laboratory’s discretion.

Not Approved requests: Ordering provider will be notified that testing will not be pursued and reason(s) will be shared. Please provide a PHIA compliant fax number or e-mail for this communication.

Test Indications: Dependent on genetic test being ordered. Refer to Requisition.

Test Approval Requirements: Contact Lab Genetic Counsellor at GenomicsLabGC@sharedhealthmb.ca or ph: 204-787-4033 with any questions.
 

Preferred Device #2 for Blood samples: Microtainer(s) - EDTA NO GEL 0.5 mL to fill line, Quantity: 2-4

Preferred Device #1 for Amniotic Fluid samples:  Sterile 15 mL Corning Polypropylene Conical Tubes, Quantity: 2-3

Contact Laboratory Genetic Counsellor at GenomicsLabGC@sharedhealthmb.ca or ph:204-787-4033 regarding collection devices for alternate samples.