Lab Information Manual

Laboratory:

Genomics (CYTOGENETICS)

Test Name:

GENOMICS PRENATAL TESTING - (Amf)

Test Code: GENO

Clinical Information:

Prenatal analysis is primarily performed on amniotic fluid. The type of analysis to order may be based on fetal presentation, and family history.

Click on desired testing method for test specific sample and/or approval requirements:

1. Rapid Aneuploidy Detection (RAD) – For rapid detection of aneuploidy of chromosomes 13, 18, 21, X & Y

2. Chromosome Analysis – For detection of possible inherited chromosome abnormalities

o Xp22.3 (STS deletion) is available for known high-risk couples

o Other prenatal FISH requests require lab pre-approval

4. Microarray – For detection of small gains or losses of chromosome material not detectable by conventional cytogenetic techniques

5. Out of Center Genetic Testing - Requires “Out-of-center Genetic testing requisition (R250-10-103) funding application

Collection Devices:

Contact the laboratory for prior approval and to obtain specimen requirements or if sending an alternative sample (such as fetal blood from PUBS).

Note that extracted DNA samples can only be accepted from accredited laboratories.

Specimen Required:

Referral:

Requisition:

Reference Values:

Availability:

Prenatal samples can be received weekdays and Saturday: 0800h - 1600h; Closed Sundays and statutory holidays.