Lab Information Manual

Laboratory:

Genomics

Test Name:

MATURITY ONSET DIABETES OF THE YOUNG (MODY) - HNF4A, GCK, HNF1A GENES - (B)

Test Code: MD

Clinical Information:

Testing done for confirmation of suspected diagnosis of Maturity Onset Diabetes in the young. Test request limited to geneticist and endocrinologist. Clinical presentation determines which gene will be tested. Genes tested are HNF1A, glucokinase (GCK) or HNF4A. All out-of-province testing subject to final laboratory approval. For more information, refer to: http://projects.exeter.ac.uk/diabetesgenes/mody/diagnostic/guidelines.htm

Collection Devices:

Preferred Device:	2 - EDTA 4 mL NO GEL Tube(s) - Full Tube Collection EDTA 4 mL NO GEL Tube(s) - Full Tube Collection Manufacturer: Becton Dickinson & Company Catalogue #: 367861
Alternate Device:	6 - Microtainer(s) - EDTA, NO GEL (0.5 mL) to fill line Microtainer(s) - EDTA, NO GEL (0.5 mL) to fill line Manufacturer: Becton Dickinson & Company Catalogue #: 363706

Specimen Required:

Blood: 8.0 mL

Pediatric Blood: 3.0 mL

Specimen must be kept at room temperature.

Referral:

Requisition:

_SH Molecular Diagnostic Lab Test Requisition (R250-10-09)

Reference Values:

An interpretive report from the reference laboratory will be forwarded to the physician.

Availability:

Extracted DNA is forwarded to an out-of-province laboratory for testing, if approved. Turnaround time is estimated to be 14 to 16 weeks.