| Laboratory: | Clinical Biochemistry |
| Test Name: |
DOXEPIN - (P)
Test Code:
MIS8
|
| Clinical Information: |
Test Indications: Doxepin is a tricyclic antidepressant used for treatment of psychoneurotic patients with depression or anxiety, and depression or anxiety associated with alcoholism or organic disease.
Nordoxepin (N-desmethyldoxepin) is the major metabolite and is usually present at concentrations equal to doxepin. Report includes concentrations of both doxepin and N-desmethyldoxepin Like other tricyclic antidepressants, the major toxicity of doxepin is expressed as cardiac dysrhythmias. Patient Preparation Instructions: Therapeutic ranges should be determined in specimens drawn at trough immediately before next dose. collect blood within 1 hours prior to next dose or at least 12 hours after last dose. |
| Collection Devices: |
Preferred Device:
Do not use separator gel.
|
| Specimen Required: |
Plasma: 2.0 mL
Serum collected without gel is also acceptable. |
| Referral: |
Serum: 2.0 mL
|
| Requisition: | |
| Reference Values: |
In-Common Laboratories Reference Values
|
| Availability: |
Within 10 Days
|
| See Also: | |
| More Information: |
Specimens that are obtained from gel tubes are not acceptable and will be rejected, as the gel absorbs the drugs and will lead to falsely decreased concentrations. Separate plasma or serum as soon as possible and no longer than 2 hours from time of collection and freeze. Send frozen specimens to In-Common Laboratories (Test ID: DOX).
|