Laboratory: Clinical Biochemistry
Test Name:
TOBRAMYCIN - (P)
Test Code: TOBR
Clinical Information:
Trough sample: 45 minutes prior to the next dose.  Peak sample: 20 – 40 minutes post tobramycin infusion.
Falsely elevated results can occur with patients co-administered either amikacin or kanamycin:
100 mg/L serum amikacin = tobramycin assay result of 1.5 mg/L
100 mg/L serum kanamycin = tobramycin assay result of 5.3 mg/L
Collection Devices:
Do not use separator gel.
Specimen Required:


Plasma: 2.0 mL
Pediatric Plasma: 0.3 mL

Stability 3 days refrigerated, 1 month frozen
Referral:

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
Requisition:
Reference Values:
TRADITIONAL DOSE      
Trough: mg/L Peak: mg/L
  Therapeutic: 0.5-2.0   Therapeutic: 6.0-10.0
  Toxic: >2.0   Toxic: >10.0
       
HIGH DOSE      
Trough: mg/L Peak: mg/L
  Therapeutic: <1.0   Therapeutic: 14-20
(mg/L = μg/mL)
Availability:
Stat or Routine
See Also:
More Information: