Laboratory: Clinical Biochemistry
Test Name:
AMITRIPTYLINE - (P)
Test Code: AMTP
Clinical Information:
Test performred at: St Boniface Hospital by Shared Health Clinical Biochemistry Laboratory using a HPLC-DAD method.

Reports will include concentration of both amitriptyline and nortriptyline since the latter drug is a metabolite and both are pharmacologically active as antidepressants.  Collect blood approximately 10 hours after last dose. 
 
For more information see:
Collection Devices:
Do not use separator gel.
Specimen Required:


Plasma: 2.0 mL

Serum collected without gel is also acceptable.
Referral:
Serum: 2.0 mL
Requisition:
Reference Values:
For amitriptyline plus nortriptyline
Therapeutic:        125-200 μg/L
Toxic:                   >500 μg/L                 (μg/L = ng/mL)
Availability:
Once Per Week
See Also:
More Information:
Collection tubes containing barrier gel cannot be used.