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Laboratory: Clinical Immunology
Test Name:
MYELOPEROXIDASE ANTIBODY (MPO) - (S)
Test Code: MPO
Clinical Information:
Testing is performed at St. Boniface Hospital Immunology Lab using an enzyme-linked immunosorbent assay (ELISA).
 
The ELISA test kit provides a quantitative in vitro assay for human autoantibodies of the IgG class against myeloperoxidase (MPO) in serum to support the diagnosis of microscopic arteritis, Polyarteritis nodosa, and Eosinophilic granulomatosis with polyangiitis (Churg-Strauss Syndrome).
Collection Devices:
Specimen Required:
Blood: 5.0 mL


Serum: 1.0 mL
Referral:
Serum: 1.0 mL

Separate serum and ship refrigerated, or frozen if greater than 7 days from time of collection.
Requisition:
Reference Values:
0 – 19 RU/ml
A negative result does not necessarily exclude autoimmune disease.  Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings.
Availability:
Weekdays
TAT 5-7 Days
See Also:
More Information:
MPO reportable range: 2 – 200 RU/ml