| Laboratory: | Clinical Immunology |
| Test Name: |
PARIETAL CELL ANTIBODY PCA - (S)
Test Code:
PCA
|
| Clinical Information: |
Test performed at: St. Boniface Hospital, Immunology Lab, using and indirect Immunofluorescence assay (IFA). Serum samples are initially screened at a 1:10 dilution.
This test kit provides semiquantitative in vitro determination of human antibodies of immunoglobulin class IgG against parietal cells in patient samples to support the diagnosis of chronic-atrophic gastritis, pernicious anemia, funicular myelosis, and various autoimmune endocrinopathies. |
| Collection Devices: |
Preferred Device:
|
| Specimen Required: |
Blood: 5.0 mL
Serum: 1.0 mL
|
| Referral: |
Serum: 1.0 mL
Separate serum and ship refrigerated or frozen if greater than 7 days from time of collection.
|
| Requisition: | |
| Reference Values: |
PCA: <1:10 Titre (Negative)
A negative result does not necessarily exclude autoimmune disease. Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings. |
| Availability: |
Weekdays
Laboratory Hours of Operation: Mon-Fri, 0800-1615, excluding holidays. PCA TAT: within 10 days
|
| See Also: | |
| More Information: |
Positive results will also be accompanied by a Titre.
Autoantibodies against mitochondria (AMA) may lead to incorrect evaluation results. The substrate primate stomach is therefore preincubated with glycine urea buffer to reduce AMA-specific fluorescence. |