|Laboratory:||Clinical Biochemistry (METABOLIC)|
TRANSFERRIN ISOELECTROFOCUSING (TIEF) - (S)
Test Code: TIEF
Test Indications: Screening for N-linked congenital disorders of glycosylation.
THIS TEST IS NOT SUITABLE FOR ALCOHOL CONSUMPTION.
The congenital disorders of glycosylation (CDG) are a rapidly expanding group of metabolic syndromes with a wide spectrum of symptoms and severity. CDG type I is associated with disruption in the synthesis of the lipid-linked oligosaccharide precursor whereas CDG type II is linked to the malfunctioning trimming/processing of the protein-bound oligosaccharide.
This test is qualitative only. This test can NOT pick up rare forms of glycosylation disorders.
For an abnormal result, the sample will be sent to a reference lab for quantitation (reflex test). For out of province customer: the billing will be done accordingly.
Method: Transferrin isoelectric focusing on a polyacrylamide gel done by Metabolic Lab at HSC.
For questions/information: Call Metabolic Lab at 204-787-4530 and ask for the Biochemical Geneticist.
Serum: 1.0 mL Pediatric: 0.3 mL minimum
Stability: see below
Store and ship refrigerated or frozen to the Metabolic Lab (HSC).
Send a clear copy of the original requisition with the sample.
Stability: see below.
A descriptive report will be sent.
Within 5 Weeks
If you have any questions, please communicate with the Metabolic Lab (HSC): 204-787-4530
Reject due to: Gross hemolysis
Stability: 3 months refrigerated or frozen
Reflex test send to Mayo Clinic Laboratories
Test ID: CDGN
CPT Code: 83789