TRIMIPRAMINE - (P)
Test Code: MIS6
Test Indications: Trimipramine is a tricyclic antidepressant with additional anxiety-reducing sedative activity. Risk of toxicity increases when concentrations >500 ng/mL. Serious adverse effects include coma, seizures, and QRS prolongation with ventricular dysrhythmias.
Patient Preparation Instructions: Therapeutic ranges should be determined in specimens drawn at trough immediately before next dose. collect blood within 1 hours prior to next dose or at least 12 hours after last dose.
Do not use separator gel.
Plasma: 2.0 mL
Serum collected without gel is also acceptable.
Serum: 2.0 mL
In-Common Laboratories Reference Values
Within 10 Days
Specimens that are obtained from gel tubes are not acceptable and will be rejected, as the gel absorbs the drugs and will lead to falsely decreased concentrations. Separate plasma or serum as soon as possible and no longer than 2 hours from time of collection and freeze. Send frozen specimens to In-Common Laboratories (Test ID: TRIMI).