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Laboratory: Clinical Immunology
Test Name:
C1 ESTERASE INHIBITOR - (S)
Test Code: CEI
Clinical Information:
Alternate Name(s): C1 Inactivator, C1 Inhibitor

C1 Esterase Inhibitor is a major regulator of the inflammatory response.  Measurement of C1 Esterase Inhibitor aids in the diagnosis of hereditary and acquired angioedema which are the most common complement deficiencies.
 
Values should be used in conjunction with other laboratory and clinical findings.
 
Collection Devices:
Specimen Required:
Serum: 1.0 mL

Refrigerated: 21 days
Frozen: 30 days
Referral:
Serum: 1.0 mL

Shipping & Storage: Separate serum and ship refrigerated, or frozen if greater than 14 days from time of collection.

Testing Laboratory (MB): Health Sciences Centre Immunology Laboratory
Requisition:
Reference Values:
≥6 mo: 0.21 – 0.38 g/L
 
Studies in children show that adult levels of C1 inhibitor are reached by 6 months of age.  Adult reference values adopted from Binding Site, Optilite C3c Kit, INS023.OPT, ver 13th August 2020.
 
Reference values have not been established for patients that are less than 6 months of age. 

Method of Analysis: Turbidimetry – Binding Site Optilite
Availability:
Within 1 Week
See Also:
More Information:
Reportable Range: 0.08 – 0.88 g/L