View Test

Laboratory:

Clinical Biochemistry

Test Name:

THYROPEROXIDASE ANTIBODIES (ANTI-TPO) - (P)

Test Code: TPO

Clinical Information:

Test Indications: This test is used to assist in the diagnosis of thyroid autoimmune disorders and to differentiate autoimmunity from nonautoimmune goitre or hypothyroidism. High anti-TPO titres are found in up to 90% of patients with chronic Hashimoto's thyroiditis. In Graves disease, 70% of the patients have an elevated titre.
Patient Preparation Instructions: Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose.

Collection Devices:

Preferred Device:	1 - Li Heparin Plasma Separator Tube(s) - Full Tube Collection Li Heparin Plasma Separator Tube(s) - Full Tube Collection Manufacturer: BD (Becton Dickinson) Catalogue #: 367962
Alternate Device:	1 - Microtainer(s) - Li Heparin PST (0.6mL) to fill line Microtainer(s) - Li Heparin PST (0.6mL) to fill line Manufacturer: Becton Dickinson & Company Catalogue #: 365987

Specimen Required:

Plasma: 2.0 mL

Pediatric Plasma: 0.2 mL

Specimen Stability:

Refrigerated: 8 days

Frozen: 2 years

Referral:

Serum: 2.0 mL

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)

Requisition:

_SH General Endocrinology Requisition (R250-10-76)

_SH Specialized Endocrinology Requisition (R250-10-77)

Reference Values:

< 34 IU/mL

Availability:

Daily