Laboratory: Clinical Biochemistry
Test Name:
INSULIN-LIKE GROWTH FACTOR 1 (IGF-1) and INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 (IGFBP-3) GROWTH PANEL - (S)
Test Code: MISC
Clinical Information:
IGF-1 measurement has superior diagnostic sensitivity and specificity compared with IGFBP-3.  IGFBP-3 should, therefore, be combined with IGF-1 testing.  The combination of IGF-1 & IGFBP-3 measurements is superior to determining either analyte alone in the diagnosis of growth hormone deficiency and resistance, and in the monitoring of recombinant hGH therapy.  IGFBP-3 adds little, if anything to IGF-1 testing in the diagnosis and follow-up of acromegaly and gigantism.
Collection Devices:
Send without delay to laboratory for processing.
Specimen Required:


Serum: 1.0 mL
Pediatric Serum: 0.5 mL
Referral:
Requisition:
Reference Values:
Age specific ranges on patient report.
Availability:
Within 3 or 4 Days
See Also:
More Information:
Spin down promptly and aliquot equally into 2 plastic transport vials.  Indicate patient’s age and sex.  Store and ship frozen to Mayo Medical Laboratories.  Mayo Test ID:  IGFGP (36365)