View Test

Laboratory:

Clinical Biochemistry

Test Name:

SEX HORMONE-BINDING GLOBULIN (SHBG) - (P)

Test Code: SHBG

Clinical Information:

Test Indications: This test is used for the differential diagnosis and followup of female patients with symptoms of hyperandrogenism. It can be used to calculate the free androgen index (FAI) from the ratio of total testosterone (T) to SHBG. This estimates the approximate amount of free testosterone as there is a direct correlation between calculated FAI and free testosterone level.
Patient Preparation Instructions: Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose.

Collection Devices:

Preferred Device:

1 - Li Heparin Plasma Separator Tube(s) - Full Tube Collection

Li Heparin Plasma Separator Tube(s) - Full Tube Collection
Manufacturer: BD (Becton Dickinson)

Catalogue #: 367962

Specimen Required:

Plasma: 2.0 mL

Stability 7 days refrigerated, 12 months frozen

Referral:

Serum: 2.0 mL

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)

Requisition:

_SH General Endocrinology Requisition (R250-10-76)

_SH Specialized Endocrinology Requisition (R250-10-77)

Reference Values:

Female: 16-120 nmol/L
Male: 10-73 nmol/L

Availability:

Daily