Laboratory: Clinical Biochemistry  (METABOLIC)
Test Name:
HOMOVANILLIC ACID (HVA) - (U)
Test Code: HVA
Clinical Information:
Urine VMA and HVA are recommended for investigation for Neuroblastoma in infants and children.  For investigation of Pheochromocytoma the analysis of urine metanephrines is recommended because of higher sensitivity.
Collection Devices:
Specimen Required:
Urine: 10.0 mL
Pediatric Urine: 5.0 mL
Referral:
Requisition:
Reference Values:
Random and 24 hr specimens
Age:                   μmol/mmol creatinine
< 1 yr                            ≤ 21.7
1 yr                               ≤ 18.6
2 - 4 yr                          ≤ 15.5
5 - 9 yr                          ≤ 9.3
10 - 14 yr                      ≤ 5.6
 > 14 yr                         ≤ 6.2  
Availability:
Within 10 Days
See Also:
More Information:
Performed at Health Sciences Centre by Shared Health  Biochemical Genetics Laboratory using UPLC/MS/MS.  This is a laboratory developed test.