Laboratory: Clinical Biochemistry
Test Name:
Test Code: TRPT
Clinical Information:
Tryptase is the most abundant protein in mast cells. Mast cells play a central role in inflammatory processes and are activated during allergic reactions. Tryptase determination is used for assessing mast cell activation that may occur as a result of anaphylaxis or allergen challenge. Peak values are typically reached 15 to 120 minutes after onset of anaphylaxis and return to baseline level within 3 to 6 hours. Chronic elevated tryptase levels are often seen in patients with systemic mastocytosis.
Collection Devices:
Specimen Required:

Plasma: 0.5 mL
Pediatric Plasma: 0.25 mL

Stability 7 days refrigerated, 1 year frozen
Serum: 2.0 mL

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
Reference Values:
0 - 12  μg/L
Within 2 Weeks
See Also:
More Information: