Laboratory: Clinical Biochemistry
Test Name:
Test Code: ALAU
Clinical Information:
Test Indication: This test may be of use in the differential diagnosis of porphyria.

Collection Devices:
Preferred Device:
1 - Urine Collection Container - 24 h  - Preferred Device: Collected into an amber container with 5 g sodium carbonate as preservative. Bring container to Biochemistry for preservative. Keep refrigerated during collection.
Alternate Device:
1 - Urine Collection 12 mL Tube  - Alternative Device: Fresh random urine acceptable but not preferred.
Collected in a container protected by light, without preservative.
Specimen Required:
Urine: 10.0 mL
Pediatric Urine: 5.0 mL
Urine: 10.0 mL
Pediatric Urine: 5.0 mL

Store and ship refrigerated to HSC Clinical Chemistry - MS5.
24hr urine:  Measure and record urine volume.  Pour off a 3 mL aliquot for urine creatinine. Pour off a separate aliquot into a container protected by light for ALA analysis.
Random urine:  Within 4 hours of collection, pour off an aliquot for ALA analysis, which is to be protected from light.  Make a separate 3 mL aliquot for urine creatinine.
Reference Values:
                        μmol/mmol creatinine
1 - 8 y:              2.0-5.3
9 - 17 y:            1.3-4.6
>17 y:               < 4.7 
Within 2 Weeks
Please contact Metabolic Laboratory (204)-787-4530 or Clinical Chemist on duty (pager 204-931-2980) to arrange for priority analysis in the case of suspected acute porphyria.
See Also:
More Information:
Performed at Health Sciences Centre by Shared Health Biochemical Genetics Laboratory using UPLC/MS/MS.  This is a laboratory developed test.