| Laboratory: | Clinical Biochemistry (AUTOMATED) | |||||||||||||||||||||||||||
| Test Name: |
ALKALINE PHOSPHATASE (ALP), Rural Sites (ORTHO), excluding Westman Lab - (P)
Test Code:
ALKP
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| Clinical Information: |
Serum alkaline phosphatase consists of four structurally similar enzymes (isoenzymes) depending where it is produced: liver-kidney-bone type, intestinal, placental and germ cell. The liver-kidney-bone type is particularly important. It is elevated in liver disease, disorders of the skeletal system, with fractures, and malignant tumors. Alkaline phosphatase activity is also seen in children and juveniles due to osteoblast activity associated with accelerated bone growth.
ALP testing is used for diagnosing and monitoring the treatment of liver, bone, intestinal and parathyroid diseases. Patient preparation instructions: This test is unaffected by multivitamins (45–125 µg biotin) or biotin-only supplements. |
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| Collection Devices: |
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| Specimen Required: |
Plasma: 2.0 mL
Stability 7 days refrigerated, 2 months frozen |
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| Referral: |
Serum: 2.0 mL
Shipping & Storage: Samples must be transferred to an aliquot tube and stored/shipped · Refrigerated if off-site testing to be performed within 48 hours of collection · Frozen if testing to be performed after 48 hours See #110-10-05 Serum / Plasma Separation Procedure & Transport |
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| Requisition: | ||||||||||||||||||||||||||||
| Reference Values: |
If ALP less than or equal to 30 U/L: “Patients with low alkaline phosphates levels: A low level can occur in various medical conditions and may be a marker for hypophosphatasia, a now potentially treatable disorder of bone mineralization. For further information please contact the metabolic geneticist on call through HSC paging (787-2071).” Method of Analysis: Roche Enzymatic rate |
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| Availability: |
Daily
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