| Laboratory: | Clinical Biochemistry (SENDOUTS) |
| Test Name: |
INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 (IGFBP-3) - (S)
Test Code:
MISC
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| Clinical Information: |
IGF-1 measurement has superior diagnostic sensitivity and specificity compared with IGFBP-3. IGFBP-3 should, therefore, be combined with IGF-1 testing. The combination of IGF-1 & IGFBP-3 measurements is superior to determining either analyte alone in the diagnosis of growth hormone deficiency and resistance, and in the monitoring of recombinant hGH therapy. IGFBP-3 adds little, if anything to IGF-1 testing in the diagnosis and follow-up of acromegaly and gigantism.
All other requests must be approved by a clinical biochemist using the designated test approval form.
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| Collection Devices: |
Preferred Device:
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| Specimen Required: |
Serum: 2.0 mL
Pediatric Serum: 1.0 mL
Special Processing: Centrifuge sample immediately. Aliquot and freeze. Indicate patient's age and sex. Specimen Stability: Ambient: 72 hours Refrigerated: 72 hours Frozen: 14 days |
| Referral: |
Pediatric volume: 0.8 mL
Shipping & Storage: Store and ship frozen. Avoid repeated freeze-thaw cycles. Referred Out Location: Specimen referred from HSC-MS5 to: Mayo Clinic Laboratories 3050 Superior Dr. NW Rochester, MN 55901 Phone: 800-533-1710 Test ID: IGFB3 |
| Requisition: | |
| Reference Values: |
Age specific ranges on patient report.
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| Availability: |
Within 1 Week
See SOP F10-50-45D Approved Physicians for Specialist Endocrinology Requisition
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| See Also: | |
| More Information: |