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Laboratory: Clinical Immunology
Test Name:
PROTEINASE 3 ANTIBODY (PR3) - (S)
Test Code: PR3
Clinical Information:
Testing is performed at St. Boniface Hospital Immunology Lab using an enzyme-linked immunosorbent assay (ELISA).
 
The ELISA test kit provides a quantitative in vitro assay for human autoantibodies of the immunoglobulin class IgG against proteinase 3 (PR3) in serum to support the diagnosis of Granulomatosis with polyangiitis (Wegener's granulomatosis)
Collection Devices:
Specimen Required:
Blood: 5.0 mL


Serum: 1.0 mL
Referral:
Serum: 1.0 mL

Separate serum and ship refrigerated, or frozen if greater than 7 days from time of collection.
Requisition:
Reference Values:
0 – 19 RU/ml
A negative result does not necessarily exclude autoimmune disease.  Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings.
Availability:
Weekdays
TAT 5-7 Days
See Also:
More Information:
PR3 reportable range: 2 – 200 RU/ml