Lab Information Manual

Laboratory:

Clinical Biochemistry

Test Name:

ALPHA-FETOPROTEIN (AFP) - (CSF)

Test Code: MSFL

Clinical Information:

Test Indications: This test is used for the diagnosis and management of intracranial germ cell tumors.
Recommendations: An Update on the Clinical Diagnostic Value of Beta-HCG and AFP for Intracranial Germ Cell Tumors. Eur J Med Res 2016, 21:10
Patient Preparation Instructions: Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose.
Additional Information: The test method used is an Electrochemiluminescence (ECLIA) assay manufactured by Roche Diagnostics Inc. and performed on the Cobas Elecsys system.
Patient results determined by different assay manufacturers or methods are not comparable and cannot be used interchangeably for patient monitoring.

Collection Devices:

Preferred Device:	1 - Sterile 15 mL Screw Cap Collection Container Sterile 15 mL Screw Cap Collection Container Manufacturer: Catalogue #:
Alternate Device:	1 - Sterile 15 mL Screw Cap Conical Tube Sterile 15 mL Screw Cap Conical Tube Manufacturer: Becton Dickinson Catalogue #:

Specimen Required:

Cerebrospinal Fluid: 1.0 mL

Stability 24 hours refrigerated, 7 days frozen

Referral:

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)

Requisition:

_SH Body Fluid Requisition (R250-10-53)

Reference Values:

≤ 1.0 µg/L

Availability:

Daily or Stat