| Laboratory: | Clinical Immunology |
| Test Name: |
ENDOMYSIAL ANTIBODY (IgA) - (S)
Test Code:
TTGA
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| Clinical Information: |
Testing is performed at St. Boniface Hospital Immunology Lab using an indirect Immunofluorescence assay (IFA). Testing is ONLY performed as a reflex test for samples with a positive tTG IgA.Serum samples are initially screened at a 1:10 dilution.
This test kit is designed for the semiquantitative in vitro determination of human antibodies of immunoglobulin classes IgA against endomysium in patient samples for the diagnosis of gluten-sensitive enteropathy (GSE; young children: coeliac disease, adults: nontropical sprue) and Duhring's dermatitis herpetiformis. |
| Collection Devices: |
Preferred Device:
|
| Specimen Required: |
Blood: 5.0 mL
Serum: 1.0 mL
|
| Referral: |
Serum: 1.0 mL
Separate serum and ship refrigerated, or frozen if greater than 7 days from time of collection.
|
| Requisition: | |
| Reference Values: |
AEMA: <1:10 Titre (Negative)
A negative result does not necessarily exclude autoimmune disease. Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings. |
| Availability: |
Weekdays
Laboratory Hours of Operation: Mon-Fri, 0800-1615, excluding holidays. AEMA TAT: within 4 days
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| See Also: | |
| More Information: |
Positive results will also be accompanied by a Titre.
Note: Levels may become undetectable after a gluten free diet is initiated. |