| Laboratory: | Clinical Immunology |
| Test Name: |
TISSUE TRANSGLUTAMINASE IgA (TTG-A) - (S)
Test Code:
TTGA
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| Clinical Information: |
Testing is performed at St. Boniface Hospital Immunology Lab using an enzyme-linked immunosorbent assay (ELISA).
The ELISA test kit provides a quantitative in vitro assay for human autoantibodies of the IgA class against tissue transglutaminase in serum to support the diagnosis of gluten-sensitive enteropathy (celiac disease) and dermatitis herpetiformis Duhring. |
| Collection Devices: |
Preferred Device:
1 - Serum Separator (SST) Tube(s) - Full Tube Collection
|
| Specimen Required: |
Blood: 5.0 mL
Serum: 1.0 mL
|
| Referral: |
Serum: 1.0 mL
Separate serum and ship refrigerated, or frozen if greater than 7 days from time of collection.
|
| Requisition: | |
| Reference Values: |
0 – 19 RU/ml
A negative result does not necessarily exclude autoimmune disease. Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings. A positive TTGA test will reflex to Endomysial antibody testing by Immunofluorescence (see Endomysial Antibody). |
| Availability: |
Weekdays
TAT: 5-7 Days
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| See Also: | |
| More Information: |
TTG IgA reportable range: 2 – 200 RU/ml
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