L-ASPARAGINASE ACTIVITY - (P)

Test Code: MIS8

Test Indications:  This test is indicated to monitor L-asparaginase activity in children with acute lymphoblastic leukemia (ALL) receiving PEG-Asparaginase.
Recommendations:   This test is only ordable by Peadiatric Oncologists. All requests require Biochemist approval. Use form F260-11-02 Biochemistry Approval for Test Referral to request approval. 

Specimens that are obtained from gel tubes are not acceptable and will be rejected.

CHU Sainte-Justine Laboratory Reference Values
 
English translation of generic comment on the original report:
"Targeted values for a patient depend on many factors like the pathophysiological state, dose taken and the type of Aspaarginase. This is to ordering physician to determine the optimal value for their patient. However, the ordering physician may consult a professional at Unite de Pharmacologie at CHU Sainte-Justine."

Within 1 Week

Centrifuge the blood sample at 1100-1300 x g for 10 minutes at 25º C. Vial labels must include
the name of the patient, date and time the specimen was collected, type of sample (serum
or plasma) and the form of L-asparaginase received by the patient (EColi, Erwinia or
PEG) .Immediately place the cryotube in a freezer maintained at -70 ºC or lower until packaged for shipment.
Samples stored at room temperature for longer than 2 hours are not suitable for testing and will be rejected. Frozen samples should be shipped on Dry ice to:
Laboratory of the Clinical Pharmacology Unit Department of Biochemistry, Room 2943
CHU Ste-Justine
3175, Ste-Catherine Road
Montreal (Quebec)
Canada H3T 1C5
Phone: (514) 345-4931 ext 5645
Fax: (514) 345-4803