| Laboratory: | Clinical Biochemistry (SPECIAL CHEMISTRY) | ||||
| Test Name: |
IGF-1 (INSULIN-LIKE GROWTH FACTOR 1) - (S)
Test Code:
IGF1
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| Clinical Information: |
Test Indications: This test is used for the evaluation of growth hormone deficiency or excess in children & adults, monitoring of growth hormone treatment, or the follow-up of individuals with acromegaly and gigantism.
Ordering is available only for physicians approved to use the Specialized Endocrinology Requisition See F10-50-45D Approved Physicians for Specialist Endocrinology Requisition |
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| Collection Devices: |
Red top no gel serum tubes are also acceptable.
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| Specimen Required: |
Serum: 1.0 mL
Pediatric Serum: 0.3 mL
Special Processing: Separate plasma/serum from cells immediately (<60 min) and freeze. Specimen Stability: Refrigerated: 6 hours Frozen: many months at -20C (avoid repeat freeze-thaw cycles) Thawed samples must be analyzed within 3 hours |
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| Referral: |
Shipping & Storage: Serum must be transferred to an aliquot tube and stored/shipped frozen.
Thawed samples are not suitable for testing.
See #110-10-05 Serum / Plasma Separation Procedure & Transport
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| Requisition: | |||||
| Reference Values: |
Method of Analysis: DiaSorin Chemiluminescence
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| Availability: |
Within 1 Week
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| See Also: | |||||
| More Information: |
Interpretation & Assay Interferences: The assay is not affected by concentrations of bilirubin up to 20 mg/dL, hemoglobin up to 1000 mg/dL, or triglycerides up to 3000 mg/dL.
No cross-reactivity was shown with proinsulin up to 140000 ng/mL, insulin up to 12000 µIU/mL, HGH up to 1000 ng/mL, and IGF-II up to 10000 ng/mL.
Although HAMA-neutralizing agents are added, extremely high HAMA (human anti-mouse antibodies) concentrations may occasionally influence results.
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