Laboratory: Clinical Immunology
Test Name:
ASCA (SACCHAROMYCES CEREVISIAE ANTIBODY) IgA and IgG - (S)
Test Code: ASCA
Clinical Information:
 
Test performed at St. Boniface Hospital Immunology Lab using the enzyme immunoassay (EIA) technique. Results are reported as two separate assays: ASCA (IgA) and ASCA (IgG).
A positive for either ASCA (IgA) or ASCA (IgG) should be interpreted as a positive result.
ASCA (IgA) and ASCA (IgG) are antibodies specific to the yeast product mannan. The tests are used in the investigation of Inflammatory Bowel Disease and, in conjunction with other findings, as an indicator of Crohn’s Disease. However, only approx. 60 – 65% of Crohn’s disease patients have a detectable ASCA level.
 
** For Inflammatory Bowel Disease, please see tests listed below:
Collection Devices:
Specimen Required:
Blood: 5.0 mL


Serum: 1.0 mL
Referral:
Serum: 1.0 mL

Separate serum; store and ship serum aliquot refrigerated.  Do NOT freeze.
Requisition:
Reference Values:
ASCA IgG negative = 0 - 19.0 RU/mL
ASCA IgA negative = 0 - 19.0 RU/mL
A negative result does not necessarily exclude disease.  Positive results should not be interpreted in isolation and must be correlated with relevant clinical findings.
Availability:
Within 5 Days
See Also:
More Information:
ASCA test code orders both IgG and IgA.