Lab Information Manual

Laboratory:

Clinical Biochemistry (SENDOUTS)

Test Name:

METHYLMALONIC ACID - (U)

Test Code: MMA

Clinical Information:

Description: Methylmalonic acid measured in plasma/serum is preferred test for evaluation of methylmalonic acidemia or vitamin B12 deficiency.

See METHYLMALONIC ACID - (P)

Test Indications: This test is used for evaluating children with signs and symptoms of methylmalonic acidemia.

This test is also used for evaluating individuals with signs and symptoms associated with cobalamin deficiency (vitamin B12).

Test Approval Requirements: Approval Is not required for patients <19 years. For adults (≥19y) testing is restricted without approval to following specialties: hematology, oncology, neurology, and genetics. All other requests require test approval. Click here for the Approval for Test Referral Biochemistry for (F260-11-02).

Collection Devices:

Preferred Device:

1 - Urine Collection 12 mL Tube

Urine Collection 12 mL Tube
Manufacturer: Sarstedt Canada Inc. (vendor)

Catalogue #:

Specimen Required:

Urine: 4.0 mL

Pediatric Urine: 1.2 mL

Special Processing: Store and send frozen. Do NOT ship frozen 100 mL containers

Specimen Stability:

Ambient: 21 days

Refrigerated: 28 days

Frozen: 28 days

Referral:

Referred Out Location:

Specimen referred from HSC-MS5 to:

Mayo Clinic Laboratories

3050 Superior Dr. NW

Rochester, MN 55901

Phone: 800-533-1710

Test ID: MMAU
Test Name: Methylmalonic Acid, Quantitative, Urine

Requisition:

Reference Values:

Reference Intervals: <3.60 mmol/mol creatinine

Availability:

Within 2 Weeks