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Laboratory: Clinical Biochemistry
Test Name:
Test Code: BZMG
Clinical Information:
Test performed at: Health Sciences Centre
This test is used for prognosis assessment of multiple myeloma.
Beta-2-microglobulin is a small membrane protein similar to the major histocompatibility complex proteins. It's small size allows rapid filtration through renal glomeruli and subsequent reabsorbtion in the proximal tubules. Beta-2-microglobulin levels are increased in diseases associated with increased cell turnover. It is also elevated in autoimmune diseases, inflammation, liver disease, neoplasms and malignancies such as myeloma.  
Collection Devices:
Collect a minimum of 0.5 mL pediatric blood in each microtainer.
Specimen Required:

Plasma: 2.0 mL
Pediatric Plasma: 0.3 mL

Stability 3 days refrigerated, 6 months frozen
Serum: 2.0 mL

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
Reference Values:
1.1 - 2.4 mg/L          (mg/L  x  84.7  = nmol/L)
See Also:
More Information: