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Laboratory: Clinical Biochemistry
Test Name:
DEHYDROEPIANDROSTERONE SULFATE (DHEA-SO4) - (P)
Test Code: DHAS
Clinical Information:
Test performed at: St. Boniface Hospital
Test Indications: This test is used for the differential diagnosis of female patients with clinical symptoms of hyperandrogenism. Elevated levels of DHAS are indicative of an involvement of the adrenal gland as the adrenal is the sole source of production. DHAS testing is also used in the diagnosis of congenital adrenal hyperplasia and premature adrenarche.
Patient Preparation Instructions:  Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose.
Collection Devices:
Specimen Required:


Plasma: 2.0 mL

Stability 14 days refrigerated, 12 months frozen
Referral:
Serum: 2.0 mL

Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
Requisition:
Reference Values:
AGE GROUP     FEMALE    DHAS (μmol/L) MALE    DHAS (μmol/L)     
0 - 4 wk: 0-5.4 0-5.4
5 wk - 11 mo: 0-1.5 0-1.1
12 mo - 9 y: 0-3.8 0-3.9
10 - 19 y: 0-14.5 0-15.1
20 - 29 y: 1.8-10.3 7.6-17.4
30 - 39 y: 1.2-7.3 3.3-14.1
40 - 49 y: 0.9-6.5 2.6-14.4
50 - 59 y: 0-5.4 1.9-8.4
60 - 69 y: 0-3.5 1.1-7.9
≥ 70 y: 0-2.4 0-4.7
Availability:
Daily
See Also:
More Information: