Lab Information Manual

Laboratory:

Clinical Biochemistry

Test Name:

CREATININE (iSTAT) - (B)

Test Code: CRWB

Clinical Information:

Hydroxyurea may cause a significant error in the measurement of creatinine on the iSTAT. The magnitude of the bias is independent of the creatinine level. Use alternative method. Send sample to laboratory for analysis.

Only available in rural Manitoba. For WRHA and Westman Lab see Creatinine - (P)

State whether the sample is venous or arterial.

Collection Devices:

Preferred Device:

1 - Li Heparin, NO GEL 4.0 mL Tube(s) - Full Tube Collection

Li Heparin, NO GEL 4.0 mL Tube(s) - Full Tube Collection
Manufacturer: BD (Becton Dickinson)

Catalogue #: 367884

Specimen Required:

Skin puncture: lancet and capillary collection tube (plain, lithium heparin, or balanced heparin for electrolytes and blood gases)
Venipuncture: lithium or sodium heparin collection tubes and disposable transfer device
(e.g. 1cc syringe and a 16 to 20 gauge needle)
Arterial puncture: Plain syringe or blood gas syringe with heparin and labeled for the assays performed

Referral:

Only available at sites which perform iStat testing onsite.

Requisition:

I-Stat Downtime Report (F100-10-02A)

Reference Values:

Venous & Capillary: 53 - 115 μmol/L

Arterial: 53 - 115 μmol/L

Note: Reference ranges are specific to the Abbott iStat (POC instrument)

Availability:

Turn around time (TAT): < 60 minutes

See Also:

More Information:

Interferences:

Creatinine	Substance	Concentration Producing Interference	Maximum Expected In Vivo Concentration
	Acetaminophen	For every 1 mmol/L	Increase (+) creatinine by 22 μmol/L
	Ascorbate	0.227 mmol/L	Increase (+) creatinine by 62 μmol/L
	Bromide	12.5 mmol/L	Increase (+) creatinine by 71 μmol/L from an initial Creatinine concentration of 88 μmol/L
<177 μmol/L	PCO2	> 40 mmHg	Increase (+) creatinine by 6.9% per 10 mmHg PCO2
		< 40 mmHg	Decrease (-) creatinine by 6.9% per 10 mmHg PCO2
>177 μmol/L	PCO2	> 40 mmHg	Decrease (-) creatinine by 3.7% per 10 mmHg PCO2
		< 40 mmHg	Increase (+) creatinine by 3.7% per 10 mmHg PCO2
	Hydroxyurea	100 μmol/L	Increase (+) 164 μmol/L
	Creatine	5 mg/dL creatine	Increase (+) creatinine by 18 μmol/L
	N-acetylcysteine	16.6 mmol/L	Increase (+) creatinine by 35 μmol/L