| Laboratory: | Clinical Biochemistry | ||||
| Test Name: |
THYROPEROXIDASE ANTIBODIES (ANTI-TPO) - (P)
Test Code:
TPO
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| Clinical Information: |
Test Indications: This test is used to assist in the diagnosis of thyroid autoimmune disorders and to differentiate autoimmunity from nonautoimmune goitre or hypothyroidism. High anti-TPO titres are found in up to 90% of patients with chronic Hashimoto's thyroiditis. In Graves disease, 70% of the patients have an elevated titre.
Patient Preparation Instructions: Multivitamins (45–125 µg biotin) or biotin-only supplements up to 1 mg per day do not interfere with this test. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last dose. |
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| Collection Devices: |
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| Specimen Required: |
Plasma: 2.0 mL
Pediatric Plasma: 0.2 mL
Specimen Stability: Refrigerated: 8 days Frozen: 2 years |
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| Referral: |
Serum: 2.0 mL
Samples must be transferred to an aliquot tube and stored frozen if analysis will not be complete within 48 hours (#110-10-05 Serum / Plasma Separation Procedure & Transport)
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| Requisition: | |||||
| Reference Values: |
< 34 IU/mL
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| Availability: |
Daily
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| See Also: | |||||
| More Information: |