| Laboratory: | Clinical Biochemistry (SBH ONLY - AUTO) | ||||
| Test Name: |
TSH RECEPTOR ANTIBODY (TRAb) - (S)
Test Code:
TRAB
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| Clinical Information: |
Description: TRAb is an autoantibody to the thyroid cell receptor for TSH and observed in 90% patients with Graves’ disease.
TRAb measurements may be useful in following: · Diagnosis of clinically suspected Graves’ disease · Assessment of the neonatal thyrotoxicosis risk in a fetus of female with Graves’ disease (active or treated) · Diagnosis of gestational thyrotoxicosis / recurrent Graves’ disease / normal first trimester of pregnancy · Graves’ disease relapse in treated patient · Differential diagnosis of thyrotoxicosis in patients with unclear biochemical findings or pregnancy.
Patient preparation instructions: Avoid high biotin doses (i.e. > 300 mg/day) for three days prior to specimen collection.
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| Collection Devices: |
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| Specimen Required: |
Serum: 1.0 mL
Pediatric Serum: 0.5 mL
Specimen Stability: Refrigerated: 7 days Frozen: 1 year |
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| Referral: |
Serum: 1.0 mL
Testing Laboratory (MB): St. Boniface Hospital – Clinical Biochemistry Lab
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| Requisition: | |||||
| Reference Values: |
Reference Intervals: <1.8 IU/L
Interpretation: Results ³1.8 IU/L have sensitivity of 97% and specificity of 99% for Graves’ disease. Method of Analysis: Roche Electrochemiluminescence |
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| Availability: |
Within 1 Week
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| See Also: | |||||
| More Information: |